Foot-and-Mouth Disease

DNA Priming Followed by Protein Boosting Enhances Immune Response

Published in Vaccine Weekly, March 22nd, 2000

DNA priming followed by protein boosting enhances the immune response of the vaccine to acceptable levels, reported researchers from Taiwan in a study on foot-and-mouth disease.

"Foot-and-mouth disease virus (FMDV) is the etiological agent of FMD that can cause tremendous loss to the livestock industry," reported Jeng-Jer Shieh and colleagues from the Academia Sinica, Taiwan. "The structure protein VP1 of FMDV carries critical epitopes that are responsible for the induction of anti-FMDV neutralizing antibodies and cellular immune responses."

Shieh et al. presented data from their work at the meeting Molecular Approaches to Vaccine Design, held in...

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Source: Vaccine Weekly (2000-03-22)

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