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Non-Hodgkin's Lymphoma

Immunotherapy with Epratuzumab Demonstrates Clinical Efficacy

Published in Vaccine Weekly, September 20th, 2000

Immunotherapy of non-Hodgkin's lymphoma (NHL) with epratuzumab, an anti-CD22 monoclonal antibody (MAb), has demonstrated excellent tolerability and clear clinical efficacy, according to recent study findings.

"CD22 is a B-cell specific antigen which is commonly expressed in indolent and aggressive NHL," stated John P. Leonard and colleagues from Weill Medical College of Cornell University and New York Presbyterian Hospital, and Immunomedics, Inc., and Garden State Cancer Center, New Jersey.

"Epratuzumab (Hll2 or LymphoCide), Immunomedics, Inc., Morris Plains, New Jersey) binds CD22, and in radiolabeled forms has been demonstrated to have...

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