Brain Cancer

Combination Vaccine and Radiotherapy Kills Tumors in Mice

Published in Vaccine Weekly, November 1st, 2000

Researchers in Hungary found that cytokine-expressing autologous cancer cell vaccines combined with radiotherapy effected cures in a majority of mice with brain tumors.

"The combined therapeutic effect of cytokine-expressing autologous cancer cell vaccines and local radiotherapy was studied in a murine brain tumor model," reported Katalin Lumniczky and colleagues from the National Institute for Radiobiology and Radiohygiene, Budapest. "Using an adenoviral vector system various cytokine-encoding genes were introduced into murine Gl261 cells."

Lumniczky et al. presented data from their study at the 14th European Immunology Meeting, held September...

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Source: Vaccine Weekly (2000-11-01)

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