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Leukemia

Autologous T Lymphocytes Specifically Recognize Leukemic B Cells

Published in Vaccine Weekly, February 14th, 2001

- by Michelle Marble, staff medical writer -- According to a study from Sweden, the spontaneous immunity found in some chronic lymphocytic leukemia (CLL) patients could be harnessed in a vaccine.

"This study analyzed a naturally-occurring specific cellular immunity against tumor cells in chronic lymphocytic leukemia (CLL) patients," stated M.R. Rezvany and colleagues, Karolinska Hospital. "Five out of eight patients had blood T lymphocytes able to recognize spontaneously and specifically the autologous tumor B cells (proliferation assay)."

Rezvany et al. published the results of their study in the British Journal of Hematology ("Autologous T...

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