Chlamydia trachomatis
Direct Detection Of T Cells May Characterize Immune Response
Published in Vaccine Weekly, March 7th, 2001
"We recently identified human leukocyte antigen (HLA) class I-presented epitopes in the major outer membrane protein (MOMP) of Chlamydia trachomatis that elicit cytotoxic T lymphocytes (CTL) responses in human genital tract infections," said S.K. Kim and colleagues, Yale University. "T cells possessing cytolytic activities specific for these epitopes could be detected following in vitro stimulation of peripheral blood CD8+ T cells with peptides."
Using ex vivo tetramer analysis, the...
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Source: Vaccine Weekly (2001-03-07)
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