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Cervical Cancer

Nasal Vaccine Against Human Papillomavirus May Prevent Transmission

Published in Vaccine Weekly, March 21st, 2001

by N.R. Saltmarsh, staff medical writer -- A vaccine that inhibits the growth of human papillomavirus 16 (HPV16) in mice may ultimately be used to help women stimulate their own immune systems to fight off the infection that causes cervical cancer.

Researchers have theorized that some women are naturally able to resist infection with HPV16 with the help of anti-HPV16-specific antibodies, though no adequate experimental model exists to test the theory.

"Induction of HPV16-specific cell-mediated immunity in the genital mucosa could improve the efficacy of a vaccine and a mucosal route of immunization might be necessary to do so," suggested V. Revaz and...

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