Published in Vaccine Weekly, April 4th, 2001
Measles still carries a high mortality rate in the developing world, and vaccine by injection has its own risks, including decreased stability of the vaccine upon reconstitution and possible infection from contaminated needles, noted Cynthia LiCalsi and colleagues, Dura Pharmaceuticals, San Diego, California. An aerosol delivery system, therefore, would be ideal, they think.
"The first challenge in aerosol formulation development is to produce fine particles without damaging the activity of...
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