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Measles

Aerosol Delivery Of Vaccine May Be Ideal For Developing Countries

Published in Vaccine Weekly, April 4th, 2001

by N.R. Saltmarsh, staff medical writer - A powder formulation of measles vaccine would be a practical alternative to injectable vaccine in developing countries.

Measles still carries a high mortality rate in the developing world, and vaccine by injection has its own risks, including decreased stability of the vaccine upon reconstitution and possible infection from contaminated needles, noted Cynthia LiCalsi and colleagues, Dura Pharmaceuticals, San Diego, California. An aerosol delivery system, therefore, would be ideal, they think.

"The first challenge in aerosol formulation development is to produce fine particles without damaging the activity of...

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