Pneumococcal Infection

Protein-Conjugated Polysaccharide Vaccines More Protective Than Purified Formulation

Published in Vaccine Weekly, April 4th, 2001

by N.R. Saltmarsh, staff medical writer - Polysaccharide antigens conjugated to certain proteins offer better protection against pneumococcal infection than the purified polysaccharide vaccine, according to a review study published in Current Opinion in Pediatrics.

M. Ledwith noted that the pressure to develop an effective pneumococcal vaccine has intensified, thanks growing antibiotic resistance and the lack of efficacy and long-term immunity conferred by the purified polysaccharide vaccine.

The vaccine was particularly inadequate for children younger than two, the age group most likely to be affected by Pneumococcus, Ledwith noted...

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Source: Vaccine Weekly (2001-04-04)

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