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Ebola Virus
Antibody Reactivity Boosts Virulence
April 11th, 2001
by N.R. Saltmarsh, staff medical writer - Researchers working in the United States say they may have found an answer to the question, "What makes Ebola virus so deadly'" Antibody reactivity to the virus appears to be critical to its infectivity, which in some strains results in a 100% mortality rate, reported A. Takada and colleagues working at the University of Wisconsin. "We show that antisera produced by DNA immunization with a plasmid encoding the surface glycoprotein (GP) of the Zaire strain of Ebola virus enhances the infectivity of vesicular stomatitis virus pseudotyped with the GP," said Takada and associates. ...
Source: Vaccine Weekly (2001-04-11)
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