Published in Vaccine Weekly, April 11th, 2001
Caroline Demangel and colleagues in Australia proposed that a vaccination strategy optimizing interleukin 12 (IL-12) production by antigen-presenting cells (APCs) could stimulate immunity to TB infection.
"Since dendritic cells (DC) are the critical APC for activation of CD4+ and CD8+ T cells, we examined whether stimulation of Mycobacterium bovis bacillus Calmette-Guerin (BCG)-infected DC...
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