Chlamydia

New mAb Vaccine Protects Mice From Human C. Trachomatis Strain

Published in Vaccine Weekly, July 25th, 2001

by N.R. Saltmarsh, staff medical writer - A new report in Vaccine heralds the arrival of a monoclonal antibody (mAb) vaccine that protects mice against challenge with a human urogenital strain of chlamydia.

J.A. Whittum-Hudson described the difficulties of three decades of antichlamydia vaccine research that have yet to produce a candidate that can protect against heterologous challenge or infectious challenge at more than one site.

"The majority of experimental anti-chlamydial vaccines to date have targeted the chlamydial major outer membrane protein (MOMP)," wrote Whittum-Hudson and colleagues. "Many MOMP-directed vaccine candidates have...

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Source: Vaccine Weekly (2001-07-25)

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