Skin Cancer

Tumor Vaccine Causes Regression, Reduces Metastasis In Incurable Melanoma

Published in Vaccine Weekly, November 7th, 2001

by Sonia Nichols, senior medical writer - Using a new vaccine consisting of autologous tumor cells complexed with a hapten, investigators at Thomas Jefferson University's Kimmel Cancer Center have seen marked regression of metastatic tumors in patients with surgically incurable metastatic melanoma.

In previous studies, vaccines containing autologous tumor cells that had been amended with dinitrofluorobenzene (DNP) were effective for producing cell-mediated immune responses leading to inflammatory activity at areas of metastases, according to David Berd and colleagues.

"In this study we determined whether DNP vaccine could induce regression of...

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Source: Vaccine Weekly (2001-11-07)

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