Published in Vaccine Weekly, January 9th, 2002
"Gene delivery to dendritic cells provides an intracellular source of antigen for efficient and persistent loading to MHC class I molecules capable of activating CD8+ CTLs, which play a central role in antitumor immunity," N. Okada and colleagues, Kyoto Pharmaceutical University, Japan, described in a recent report.
To date, attempts at efficient dendritic cell transduction have met with many failures and some successes. Okada and colleagues have performed research suggesting the...
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Source: Vaccine Weekly (2002-01-09)
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