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AIDS and HIV Transmission

Cytotoxic T-cell activity crucial for persistently uninfected women

Published in Vaccine Weekly, March 6th, 2002

by Michael Greer, senior medical writer - Cytotoxic T-lymphocyte activity protects women who remain uninfected with HIV despite extensive exposure, a finding that may be useful for vaccine development, researchers in the United States believe.

Dr. Joan H. Skurnick and colleagues at New Jersey Medical School in Newark, the University of Maryland in Baltimore, Rockefeller University's Aaron Diamond AIDS Research Center and New York University in New York City, the University of Alabama at Birmingham, and the University of California at San Francisco investigated the factors that confer such protection to women.

CD8 cell activity is the key factor, in...

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