Tuberculosis Vaccine

BCG vaccine elevates protective cytokine release

Published in Vaccine Weekly, March 13th, 2002

by Michael Greer, senior medical writer - The venerable and widely used Mycobacterium bovis Bacillus Calmette Guerin (BCG) tuberculosis vaccination raises protective cytokine output from immune cells, researchers in the United States report.

Dr. Amminikutty Jeevan and colleagues at the Texas A&M University System Health Science Center in College Station, Texas, and the National Cancer Institute in Frederick, Maryland, investigated the molecular effects of the BCG vaccine in animals.

The vaccine significantly heightens levels of cytokines linked to productive immune activity, Jeevan and coworkers found.

The researchers...

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Source: Vaccine Weekly (2002-03-13)

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