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AIDS Therapy

Vaccines and low daily doses of interleukin 2 may hold key to cure

Published in Vaccine Weekly, April 3rd, 2002

A new clinical trial testing an HIV vaccine together with low daily doses of interleukin 2 (IL2) - led by Dr. Kendall Smith, chief of immunology in the department of medicine at Weill Cornell Medical College - is designed to determine whether it is possible to achieve control of HIV by enhancing the body's immunity to the virus.

Smith's team has previously shown that low daily doses of the T cell growth factor IL2 can result in accelerated improvement of the immune system when given to individuals with chronic HIV infection. Now, the team is testing whether it is possible to generate protective immunity to HIV, so that antiviral drugs will no longer be...

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