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Vaccine Development

Human testing of novel vaccine to fight nicotine addiction begins

Published in Vaccine Weekly, July 17th, 2002

Nabi Biopharmaceuticals (NABI) has initiated NicVAX (nicotine conjugate vaccine) phase I testing in humans. NicVAX is a proprietary and novel investigational vaccine designed to help the body develop antibodies that bind to nicotine and block it from reaching the brain. If shown to be safe and effective in subsequent clinical trials, NicVAX may help millions of people worldwide kick their addiction to cigarettes and tobacco products.

Of the 48 million adult U.S. smokers, about 70%, or nearly 34 million people have made at least one attempt to stop, yet only 1.2 million quit permanently, according to the U.S. Centers for Disease Control and Prevention.

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