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Hepatitis B Vaccine

Waiting to vaccinate against hepatitis B may be best policy for preterm infants

Published in Vaccine Weekly, July 17th, 2002

by Sonia Nichols, senior medical writer - The results of a long-term study that followed preterm infants for several years has revealed that delaying their first hepatitis B virus (HBV) vaccination may work to their advantage.

The study compared two dosing protocols. In the first, preterm infants with low risk factors for hepatitis B virus (HBV) infection were first vaccinated within a day of birth. A control group, comprising infants born at term, also received the vaccine within 24 hours of birth. In the second protocol, infants were only vaccinated when they attained a weight of 2000 g, or a little over 4 pounds. All of the infants subsequently received two more...

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