Creutzfeldt-Jakob Disease

Vaccination delays onset of prion brain disease in mice

Published in Vaccine Weekly, July 31st, 2002

Immunization with a nontoxic genetically engineered prion, a protein that causes a group of fatal brain diseases, including mad cow disease, delayed the onset of brain disease in mice, according to a preliminary study by New York University (NYU) School of Medicine researchers and colleagues.

Other studies have shown it may be feasible to recruit the immune system to fight prion-related disease. But the new study, published in the July 2002 issue of the American Journal of Pathology, is the first to show a vaccine can delay symptoms in a natural model of prion disease in mice, according to the NYU researchers.

Mad cow disease belongs to a...

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Source: Vaccine Weekly (2002-07-31)

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