Immunization

Measles IgG4 antibody levels may distinguish natural from vaccination-induced immunity

Published in Vaccine Weekly, August 21st, 2002

by Maria G. Essig, MS, ELS, senior medical writer - The distribution of measles-specific antibodies belonging to immunoglobulin G subgroups varied among individuals who were infected with measles naturally and those who were vaccinated against the disease.

M.B. Isa and colleagues working in Argentina analyzed blood samples from 258 people to determine the prevalence of different immunoglobin G (IgG) subtypes that targeted measles antigens. Subjects either displayed natural immunity against the disease or had received a measles vaccination.

The investigators divided the subjects into one of four groups. Group 1 consisted of 54 children who were...

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Source: Vaccine Weekly (2002-08-21)

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