HIV/AIDS Vaccine

gag-based DNA vaccine effective in primates

Published in Vaccine Weekly, October 2nd, 2002

by Michael Greer, senior medical writer - An HIV DNA vaccine can produce sustained and effective cell-mediated immune responses to the virus in animals, researchers in the United States report.

Michael J. Caulfield and colleagues working at Merck Research Laboratories in West Point, Pennsylvania, evaluated several formulations of an HIV gag-based vaccine.

They found that several of the vaccine candidates tested elicited long-term antigen-specific cytotoxic T-cell activity, according to their report in the October 2002 edition of the Journal of Virology.

Caulfield and coauthors tested plasmid DNA vaccine based on...

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Source: Vaccine Weekly (2002-10-02)

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