Autoimmune Disease
Study emphasizes importance of genetic susceptibility to autoimmunity
Published in Vaccine Weekly, October 9th, 2002
"In previous studies we have established a link between cytomegalovirus (CMV) infection and an autoimmune response to the U1-70 k protein of the spliceosome in man. This autoimmune response, generally referred to as the anti-RNP (ribonucleoprotein) antibodies, is observed in about 30% of patients with systemic lupus erythematosus (SLE)," wrote J. Lipes and colleagues, Montreal General Hospital, in the journal Clinical and Experimental Immunology.
"We have also found that the CMV glycoprotein B (CMV gB) when expressed in a adenovirus vector...
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Source: Vaccine Weekly (2002-10-09)
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