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Measles Vaccine

Wild-type measles strain responsible for SSPE outbreaks in New Guinea

Published in Vaccine Weekly, October 9th, 2002

by Maria G. Essig, MS, ELS, senior medical writer - Genomic analysis revealed that outbreaks of subacute sclerosing panencephalitis (SSPE) in Papua, New Guinea, are caused by a wild-type measles virus, not the vaccine measles strain.

"A very high annual incidence of 56 per million population below the age of 20 years for subacute sclerosing panencephalitis (SSPE) has been reported from Papua New Guinea (PNG)," said Kenji Miki and colleagues working in Japan and New Guinea. "In a more recent study, we have confirmed this unusual high incidence for Eastern Highlands Province (EHP) of PNG."

The investigators found that the measles vaccination rate of...

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