AIDS Resistance

Study shows why some immune systems control HIV

Published in Vaccine Weekly, November 20th, 2002

Scientists are beginning to change their thinking about why the immune systems of most people infected with HIV cannot control the spread of the virus while the immune systems of a rare group of individuals, called long-term nonprogressors, can.

For some time, scientists thought that people who could not control HIV had too few HIV-fighting white blood cells called CD8+ T cells. However, a new study suggests the difference is not the number but the quality of these cells: both nonprogressors and others have about the same number of HIV-fighting CD8+ T cells, but the cells of nonprogressors function better.

"Understanding the mechanisms by which the...

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Source: Vaccine Weekly (2002-11-20)

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