Alzheimer Disease
Passive immunization against beta-amyloid peptide protects CNS neurons
Published in Vaccine Weekly, December 4th, 2002
M.H. Mohajeri and colleagues, University of Zurich, conducted a study in transgenic mice to "characterize the effects of the familial Alzheimer's disease-causing Swedish mutations of amyloid precursor protein (SwAPP) on the vulnerability of central nervous system neurons."
They caused the SwAPP-expressing mice to have epileptic seizures.
"The transgene expression did not change the seizure threshold, but consistently more neurons degenerated in brains of SwAPP mice...
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Source: Vaccine Weekly (2002-12-04)
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