Melanoma

T-cell clones shrink tumors

Published in Vaccine Weekly, December 11th, 2002

A preliminary clinical trial suggests that armies of T cells generated in the lab can be injected into patients to halt the spread of cancerous tumors.

The study, conducted by Dr. Cassian Yee, a researcher at the Fred Hutchinson Cancer Research Center, involved 10 people diagnosed with advanced melanoma. For each patient immune system cells able to identify and target melanoma were extracted and cloned. The cloned cells were expanded in the lab and reinjected into the patient. The results of the study showed that in five patients tumors stopped growing for up to one year and in three of the patients the tumors appeared to shrink.

"While we did not...

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Source: Vaccine Weekly (2002-12-11)

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