Infectious Disease Vaccine

Bacterial meningitis vaccine elicits protective antibody production

Published in Vaccine Weekly, January 8th, 2003

by Michael Greer, senior medical writer - A novel vaccine against Neisseria meningitidis elicits a protective humoral response in human infants, researchers in the United States report.

Kenneth T. Mountzouros and colleagues working at Wyeth Research in West Henrietta, New York, assessed the efficacy of a glycoconjugate N. meningitidis vaccine.

Antibodies produced after immunization with this vaccine candidate protected rats against bacterial meningitis, Mountzouros and coauthors found.

The researchers measured anti-N. meningitidis serogroup C capsular polysaccharide (PS) immunoglobulin G (IgG) levels in pooled...

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Source: Vaccine Weekly (2003-01-08)

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