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Diabetes Vaccine

Neurologic disorders not associated with MMR vaccination

Published in Vaccine Weekly, January 22nd, 2003

by Maria G. Essig, MS, ELS, senior medical writer - Heat shock protein 60 prevented the development of cyclophosphamide-accelerated diabetes in mice, according to a report in the Journal of Immunology.

"Nonobese diabetic (NOD) mice spontaneously develop diabetes as a consequence of an autoimmune process that can be inhibited by immunotherapy with the 60-kDa heat shock protein, with its mycobacterial counterpart 65-kDa, or with other antigens such as insulin and glutamic acid decarboxylase," explained Francisco J. Quintana and colleagues at the Weizmann Institute of Science in Rehovot, Israel. "In addition to the spontaneous disease, however, NOD mice can develop...

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