Antibody Production
Mannose-binding lectin genotype determines lectin levels and function
Published in Vaccine Weekly, February 5th, 2003
According to recent research from Australia, "The mannose-binding lectin (MBL) pathway of complement activation is an important component of innate host defense. Numerous studies have described associations between the MBL genotype, MBL levels and disease susceptibility. However, genotyping and quantitative assays used in these studies have frequently been limited, and comprehensive data examining the interaction between structural and coding MBL genetic variants, MBL antigenic levels, and MBL functional activity are lacking."
"Such data may be important for accurate planning and interpretation of studies of MBL and disease," said R. M. Minchinton and collaborators at...
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Source: Vaccine Weekly (2003-02-05)
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