Allergy Medicine Vaccine

Carbohydrate-based particles are better adjuvant than alum for allergy vaccines

Published in Vaccine Weekly, February 12th, 2003

by Maria G. Essig, MS, ELS, senior medical writer - Carbohydrate-based particles (CBP) acted as an effective adjuvant for the major timothy grass pollen allergen without causing the granulomatous tissue reaction produced by the commonly used adjuvant, alum, according to a report in the journal, Immunology.

"The occurrence of systemic anaphylactic side-effects in the course of allergen-specific immunotherapy has been strongly reduced by the adsorption of allergens to aluminum hydroxide, the most frequently used adjuvant in humans," said Hans Gronlund and colleagues at the Karolinska Institutet in Stockholm, Sweden, and the University of Vienna in Austria. "Using...

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Source: Vaccine Weekly (2003-02-12)

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