Measles Vaccine

Antibody levels remain high in macaques given Quil A-adjuvanted measles vaccine

Published in Vaccine Weekly, February 12th, 2003

According to a study from the Netherlands, "Quil A-based candidate measles vaccines have been shown to be immunogenic and protective in cotton rats and macaques. Here we studied the longevity of protective VN antibody levels induced in macaques with one dose of measles virus (MV) iscom. Inactivated MV adjuvanted with iscom-matrix or with purified Quillaja saponin QA-22 were also tested."

"All animals developed high levels of VN antibody and MV-specific IFN-gamma-producing cells," reported Koert J. Stittelaar and colleagues at the Institute of Virology at Erasmus MC in Rotterdam and the National Institute of Public Health and the Environment in Bilthoven. ...

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Source: Vaccine Weekly (2003-02-12)

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