Pediatric Vaccine

COMVAX vaccine does not increase episodes of high-pitched or prolonged crying

Published in Vaccine Weekly, February 19th, 2003

by Maria G. Essig, MS, ELS, senior medical writer - The COMVAX vaccine, meant to protect against Haemophilus influenzae* type b and hepatitis B, does not cause unusually high-pitched or prolonged crying in babies compared with infants vaccinated with its components, PedvaxHIB (Haemophilus influenzae* type b vaccine) and RECOMBIVAX HB (hepatitis B vaccine), according to a report in Vaccine.

"In a previous clinical trial comparing COMVAX with its monovalent components, PedvaxHIB and RECOMBIVAX HB, 1 of 92 comparisons of postvaccination adverse experiences revealed a higher rate of unusual, high-pitched crying following the second but not the first or third...

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Source: Vaccine Weekly (2003-02-19)

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