Radioimmunotherapy

Radioiodinated monoclonal antibody effective against high-grade glioma

Published in Vaccine Weekly, February 26th, 2003

Researchers from the United States report the "follow-up of patients enrolled in a phase II clinical trial using ¹²⁵I-MAb 425 as an adjuvant treatment for high grade gliomas. Patient median survivals support published data from an earlier preliminary report."

"From January 29, 1987 to January 25, 1997, 180 patients diagnosed with astrocytoma with anaplastic foci (AAF) and glioblastoma multiforme (GBM) were treated as outpatients with an average of three weekly intravenous or intraarterial injections of radiolabeled MAb 425," stated Jacqueline G. Emrich and colleagues at Drexel University, Temple University, and Thomas Jefferson University in Philadelphia. ...

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Source: Vaccine Weekly (2003-02-26)

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