Polio Vaccine

Pleural mesothelioma incidence not related to SV40-contaminated polio vaccine

Published in Vaccine Weekly, March 5th, 2003

by Maria G. Essig, MS, ELS, senior medical writer - People vaccinated against polio with vaccines contaminated with simian virus 40 do not appear to have an increased risk of pleural mesothelioma, according to a report in the Journal of the National Cancer Institute.

"Poliovirus vaccines that were used during the late 1950s and early 1960s were contaminated with simian virus 40 (SV40), a monkey virus that is tumorigenic in rodents," said Howard D. Strickler and colleagues at Albert Einstein College of Medicine and the National Institutes of Health. "SV40 DNA sequences have been detected in some human cancers, especially pleural mesotheliomas, although results...

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Source: Vaccine Weekly (2003-03-05)

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