HIV/AIDS Vaccine

HIV-2 genetic library vaccines ineffective in animals

Published in Vaccine Weekly, March 5th, 2003

by Michael Greer, senior medical writer - An HIV vaccine containing a "library" of viral antigens has shown disappointing results in animal experiments, researchers in the United States report.

"Immunization using genetic expression libraries may be an improvement over conventional DNA immunization using a single gene because more epitopes are simultaneously presented to the immune system," according to Christopher Locher and colleagues at the University of California at San Francisco.

Unfortunately, an HIV-2 genetic library-based vaccine offered only marginal protection to animals, Locher and coauthors found.

The researchers...

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Source: Vaccine Weekly (2003-03-05)

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