Bacillus Calmette-Guerin Vaccine
Novel vaccination strategies based on Mycobacterium bovis BCG developed
Published in Vaccine Weekly, April 30th, 2003
"In this manuscript, we will review the utilization of Mycobacterium bovis Bacille Calmette-Guerin (BCG) as a vaccine against tuberculosis (TB) and as a carrier system for heterologous antigens. BCG is one of the most widely used vaccines. Novel techniques in genome manipulation allow the construction of virulence-attenuated recombinant (r)-BCG strains that can be employed as homologous vaccines, or as heterologous antigen delivery systems, for priming pathogen-specific immunity against infectious diseases, including TB," researchers in...
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Source: Vaccine Weekly (2003-04-30)
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