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HIV/AIDS Vaccine

First AIDS vaccine tested in Africa generates low immune response

Published in Vaccine Weekly, May 7th, 2003

by Maria G. Essig, MS, ELS, senior medical writer - A preventive AIDS vaccine containing HIV-1 clade B (env and gag-pro) antigens delivered by a canarypox vector elicited a weak but detectable immune response in a significant number of HIV-negative patients, according to a report in the Journal of Infectious Diseases.

Huyen Cao at the California Department of Health Services in the United States and an international team of researchers involved in the HIV Network for Prevention Trials conducted the first preventive AIDS vaccine trial in Africa. The study involved 40 HIV-negative volunteers who received either the canaraypox/HIV-1 clade B vaccine...

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