S. Pneumoniae Vaccine
Antibodies against PsaA inhibit pneumococcal adherence to nasopharyngeal cells
Published in Vaccine Weekly, May 7th, 2003
According to published research from the United States, "The role of pneumococcal (Pnc) surface adhesin A (PsaA) in the adherence of Streptococcus pneumoniae (pneumococcus) to host cells is not well defined. We examined the effect of anti-PsaA antibodies in an inhibition of adherence assay using Detroit 562 nasopharyngeal human epithelial cells."
"Rabbit polyclonal (Pab) anti-recombinant PsaA (rPsaA) sera, a purified mouse monoclonal antibody (MAb) (MAb 6F62G8E12), and 22 healthy adult sera with known anti-PsaA IgG levels...
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Source: Vaccine Weekly (2003-05-07)
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