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Gastroenterology Vaccine

Dogs vaccinated with Ancylostoma caninum exhibit antibody response

Published in Vaccine Weekly, May 14th, 2003

Dogs vaccinated with Ancylostoma caninum exhibited a strong antibody response.

"Infection with Ancylostoma caninum, an intestinal hookworm of dogs, can cause debilitating and potentially life-threatening disease. In the current study, protective immunity to hookworm infection was induced in dogs following vaccination with irradiation-attenuated third-stage larvae (L3) with significant reductions in both worm (p<0.03) and fecal egg counts (p<0.0004) following a challenge infection," scientists in Australia report.

"Vaccination with irradiated L3 and challenge with infective L3 stimulated a dominant antibody response to antigens of...

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