Published in Vaccine Weekly, May 28th, 2003
According to recent research published in the journal Cellular Immunology, "To elicit a therapeutic antitumor immune response, dendritic cells (DCs) have been employed as a cellular adjuvant. Among various DC-based approaches, fusion of DCs and tumor cells potentially confers not only DC functionality, but also a continuous source of unaltered tumor antigens. We have recently demonstrated successful generation of fusion hybrids by a large-scale electrofusion technique."
"The immunogenicity and therapeutic potential of fusion hybrids were further analyzed...
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