Cancer Vaccine
Immune response induced by electrofusion of dendritic and tumor cells
Published in Vaccine Weekly, May 28th, 2003
According to recent research published in the journal Cellular Immunology, "To elicit a therapeutic antitumor immune response, dendritic cells (DCs) have been employed as a cellular adjuvant. Among various DC-based approaches, fusion of DCs and tumor cells potentially confers not only DC functionality, but also a continuous source of unaltered tumor antigens. We have recently demonstrated successful generation of fusion hybrids by a large-scale electrofusion technique."
"The immunogenicity and therapeutic potential of fusion hybrids were further analyzed...
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Source: Vaccine Weekly (2003-05-28)
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