AIDS Prevention

Promising preclinical results presented on vaccine

Published in Vaccine Weekly, May 28th, 2003

Researchers at Columbus Children's Hospital and its collaborators, Targeted Genetics Corp. and the International AIDS Vaccine Initiative (IAVI), have demonstrated that utilizing a recombinant adeno-associated virus (rAAV)-based HIV vaccine resulted in robust and sustained antibody and T cell immune responses in nonhuman primates (monkeys).

Data presented from extensive safety studies in animals support the safety of this vaccine, named tgAAC09. These findings support clinical development of the vaccine, and human trials are targeted to begin later this year. The findings were presented during the 2003 Pediatric Academic Societies' (PAS) annual meeting by Philip R....

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Source: Vaccine Weekly (2003-05-28)

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