Neuroblastoma

Immune cells may help deliver cancer vaccines for children

Published in Vaccine Weekly, June 4th, 2003

In a finding that could lay the groundwork for future cancer vaccines for children, cancer researchers working in cell culture have shown that modified immune cells can efficiently deliver genetic material to stimulate a desirable immune response.

Researchers from The Children's Hospital of Philadelphia and the Abramson Family Cancer Research Institute at the University of Pennsylvania manipulated immune cells called CD40-activated B cells to carry RNA produced by tumors and viruses. The RNA, which carries genetic codes from DNA, was obtained either from tumor or viral proteins. The researchers adapted an approach used in research on adults to one more appropriate for...

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Source: Vaccine Weekly (2003-06-04)

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