Cancer Vaccine
Antibody mimic CO17-1A elicits immune response in colorectal cancer patients
Published in Vaccine Weekly, June 4th, 2003
According to published research from the United States, "Monoclonal rat anti-idiotypic antibody (Ab2) BR3E4 mimicking the colorectal carcinoma (CRC)-associated epitope CO17-1A induced antigen-specific humoral and cellular immune responses in mice and rabbits."
"Ab2 BR3E4 was administered in a phase I trial to CRC patients either as intact IgG or as F(ab')2 coupled to keyhole limpet hemocyanin (KLH)," reported Brigitte Birebent and colleagues at the Wistar Institute, Thomas Jefferson University, and...
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Source: Vaccine Weekly (2003-06-04)
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