Hepatitis A Vaccine
Liposome entrapment of hepatitis A virus peptides produces effective vaccine
Published in Vaccine Weekly, June 11th, 2003
"Multiple antigen peptides (MAP) have been demonstrated to be efficient immunological reagents for the induction of immune responses to a variety of infectious agents. Several peptide domains of the hepatitis A virus (HAV) capsid proteins, mainly VP1 and VP3, are the immunodominant targets for a protective antibody response. In the present study we analyzed the immunogenic properties of a tetrameric heterogeneous palmitoyl-derivatized MAP containing two defined HAV peptide sequences, VP111-25 , and VP3102-121...
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Source: Vaccine Weekly (2003-06-11)
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