Published in Vaccine Weekly, June 11th, 2003
"Multiple antigen peptides (MAP) have been demonstrated to be efficient immunological reagents for the induction of immune responses to a variety of infectious agents. Several peptide domains of the hepatitis A virus (HAV) capsid proteins, mainly VP1 and VP3, are the immunodominant targets for a protective antibody response. In the present study we analyzed the immunogenic properties of a tetrameric heterogeneous palmitoyl-derivatized MAP containing two defined HAV peptide sequences, VP111-25 , and VP3102-121...
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