Mumps Vaccine
Low efficacy of Rubini mumps vaccine strain leads to outbreak in Singapore
Published in Vaccine Weekly, July 2nd, 2003
According to recent research published in the Journal of Medical Virology, "During 1999-2000, a sustained mumps outbreak in the highly vaccinated population in Singapore was attributed to vaccine failure associated with the Rubini vaccine strain. To explain this phenomenon, the complete nucleotide and amino acid sequences of the hemagglutinin-neuraminidase (HN) gene of eight mumps virus isolates from patients with parotitis in Singapore were determined and compared with those of known vaccine strains."
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Source: Vaccine Weekly (2003-07-02)
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