Anthrax Vaccine

Interleukins-2 and -4, but not interferon-gamma, exhibit adjuvant activity

Published in Vaccine Weekly, July 9th, 2003

by Maria G. Essig, MS, ELS, senior medical writer - Cell wall components of Bacillus anthracis Sterne did not adversely affect the immune response generated by protective antigen, the main bacterial immunogen, according to a report in FEMS Immunology and Medical Microbiology.

"The UK human anthrax vaccine consists of the alum-precipitated culture supernatant of Bacillus anthracis Sterne," stated Leslie Baillie at the University of Maryland in the United States and colleagues at the Defence Science and Technology Laboratory (DSTL) in the U.K. "In addition to protective antigen (PA), the key immunogen, the vaccine also contains a number of other...

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Source: Vaccine Weekly (2003-07-09)

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