Diarrhea Vaccine

E. coli vaccine elicits strong immune response in Bangladeshi children

Published in Vaccine Weekly, July 23rd, 2003

by Maria G. Essig, MS, ELS, senior medical writer - A vaccine containing inactivated Escherichia coli plus six colonization factors and a cholera toxin subunit elicited strong mucosal and systemic antibody responses in children in Bangladesh.

"A phase II safety and immunogenicity study of an oral-formalin inactivated enterotoxigenic Escherichia coli (ETEC) vaccine containing six colonization factors (CFA/I, CS1, CS2, CS3, CS4, CS5) and 1 mg of recombinant cholera toxin B subunit (the CF-BS-ETEC vaccine) was carried out in an urban slum of Dhaka city in Bangladesh," reported Firdausi Qadri at the International Center for Diarrheal Disease Research in...

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Source: Vaccine Weekly (2003-07-23)

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