HIV/AIDS Vaccine

AIDS vaccination strategy induces significant cellular immune responses

Published in Vaccine Weekly, July 30th, 2003

by Maria G. Essig, MS, ELS, senior medical writer - Mice primed with influenza virus Env followed by immunization with vaccinia virus (VV) expressing HIV-1 Env B stimulated a strong protective cellular immune response in the spleen and in the lymph nodes draining the genital and rectal tracts, according to a report in the Journal of Virology.

"Vaccines that elicit systemic and mucosal immune responses should be the choice to control human immunodeficiency virus (HIV) infections," stated M. Magdalena Gherardi and colleagues at the Centro Nacional de Biotecnologia in Madrid, Spain. "We have previously shown that prime-boost immunizations with influenza virus Env...

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Source: Vaccine Weekly (2003-07-30)

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