Vaccine Safety

JC virus infection increases risk of adult astrocytic brain tumors

Published in Vaccine Weekly, July 30th, 2003

Adults with antibodies to the JC virus had an increased risk of developing astrocytic brain tumors.

"Genomic sequences of the human polyomaviruses, JC virus (JCV) and BK virus (BKV), and simian virus 40 (SV40) have been reported from several types of human brain tumors, but there have been no population-based seroepidemiologic studies to evaluate the association between polyomavirus infection and brain tumors. We conducted a case-control study, nested within a prospective cohort, to investigate the association between antibodies to JCV, BKV, and SV40, as measured in serum collected 1-22 years before diagnosis and incident primary malignant brain tumors," scientists...

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Source: Vaccine Weekly (2003-07-30)

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