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AIDS and HIV

Novel adenovirus-based SIV vaccine effective in macaques

Published in Vaccine Weekly, August 6th, 2003

by Michael Greer, senior medical writer - A novel adenovirus-based vaccine against the simian version of HIV (SIV) has delivered promising results in a macaque model of infection, researchers in the United States report.

Jun Zhao and colleagues at the National Cancer Center in Bethesda, Maryland, the Duke University Medical Center in Durham, North Carolina, and Advanced BioScience Laboratories, Inc., in Kensington, Maryland "investigated the ability of a replication-competent Ad5hr-SIVenv/rev and Ad5hr-SIVgag recombinant priming/gp120 boosting regimen to induce protective immunity in rhesus macaques against pathogenic simian immunodeficiency...

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